Product

Bioreactor & fermenter for research
and development

Pilot Series
- BIOCNS P

Pilot Series – BIOCNS P is a pilot-scale cultivation system designed to reproduce lab-proven conditions and validate reliable scale-up to commercial production.

Features
  • Scalable system from lab to production
  • Selectable direct or indirect heating
  • Standard volumes from 30 L to 500 L (customizable)
  • Integrated SIP / CIP system
  • Fully automated PLC-based control
  • Advanced pH & DO cascade control
  • Selectable multi-feed system
  • MFC-based gas supply and mixing control
  • Data logging, trend analysis, and remote monitoring
  • Validation support compliant with GMP processes

BIOCNS P Series Product Code Classification

Control System

  • Intuitive HMI-based user interface
  • Real-time process monitoring
  • Simultaneous SV / PV display
  • Integration with ORP, OD, and level sensors
  • Support for Batch and Fed-Batch operation (recipe-based)
  • Multi-channel gas control via MFC
  • Automatic alarms, data logging, and trend charts
  • Integration with external equipment (mixing tanks, sampling systems, etc.)

2D/3D Design & Manufacture

Specification

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Specification Pilot
Vessel Volume 30 / 50 / 100 / 200 / 300 / 500 L - Standard type(customizable, per vessel)
Working Volume 20 / 35 / 70 / 140 / 210 / 350 L
Speed (RPM) 50 – 400 (selectable)
Motor Power (kW) 0.75 / 1.5 / 1.5 / 2.2 / 3.2 / 3.7(selectable)

General

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Item Specification / Description
Aspect Ratio 2.2 : 1(standard)
Construction STS316L, internal/external electropolished (Ra ≤ 0.6 µm)
Drive Type Top or bottom drive, mechanical or magnetic seal
Impeller 3 Rushton impellers (optional: Marine or Pitched Blade type)
Baffle 3~4 baffles, SUS316L
Agitation Control AC gear or servo motor drive, automatic PID speed control
Air Line Equipped with rotameter, SIP inlet filter (0.2 µm), and sparger
Optional Gas System Mass Flow Controller (MFC) for precise gas flow and mixing
Sterilization Indirect hot-water sterilization or steam injection (105–130 °C)
Exhaust Line Stainless-steel condenser with automatic backpressure control
Pressure Control Manual or automatic PID-based backpressure regulation
Temperature Control Ambient +3 °C – 80 °C, RTD (Pt100), PID precision control
pH Control Range 2.0–12.0 pH, Gel-type electrode, PID cascade control
DO Control 0–200 % range, Polarographic sensor, PID cascade control
Sensors pH / DO / Temperature / Pressure / Foam / Level (retractable probes)
Controller Industrial PLC large touchscreen HMI interface
Gas Supply NH₃ (Ammonia)
Software Real-time process, trend & calibration display; automatic memory backup
Communication RS-232C / USB / PC / Printer connection for data export
Data Storage pH, DO, Temp, Pressure, Agitation, Air Flow, Anti-Foam, etc.
Options Load cell for feeding control, Validation package, MFC gas module, External tank integration

Component Overview

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